Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Dave Matthews Patrick Obyedkov Guest Star Kurtwood Smith Dr. Obyedkov Guest Star Dru Mouser Arlene Guest Star Scott Weintraub Stage Manager Guest Star Tyler Patton Neurosurgeon Guest Star Kendra Cover Patient Guest Star Ingrid Sanai Buron Nurse Bev Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer, Director David Shore Executive Producer Bryan Singer Executive Producer Lawrence Kaplow Writer