Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Anne Dudek Dr. Amber Volakis Guest Star Olivia Wilde Thirteen, Dr. Remy Hadley Guest Star Peter Jacobson Dr. Chris Taub Guest Star Fred Durst Bartender Guest Star Kal Penn Dr. Lawrence Kutner Guest Star Kathryn Adams Young Doctor Guest Star Edi Gathegi Dr. Jeffrey 'Big Love' Cole Guest Star Michael Michele Dr. Samira Terzi Guest Star Andy Comeau Dr. Travis Brennan Guest Star Bobbin Bergstrom Nurse Guest Star Melinda Dahl Twin 1 Guest Star Dina Defterios Luisa Maria Guest Star Caitlin Dahl Twin 2 Guest Star Carmen Argenziano Henry Dobson Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer, Writer Bryan Singer Executive Producer Deran Sarafian Director David Straiton Director David Platt Director Greg Yaitanes Director Juan José Campanella Director Matt Shakman Director Peter Blake Writer David Foster Writer Russel Friend Writer David Hoselton Writer Sara Hess Writer Liz Friedman Writer Eli Attie Writer Thomas L. Moran Writer Garrett Lerner Writer