Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Frank Whaley Robert Elliot Guest Star Anne Dudek Dr. Amber Volakis Guest Star Olivia Wilde Thirteen, Dr. Remy Hadley Guest Star Peter Jacobson Dr. Chris Taub Guest Star Kal Penn Dr. Lawrence Kutner Guest Star Andy Comeau Dr. Travis Brennan Guest Star Edi Gathegi Dr. Jeffrey 'Big Love' Cole Guest Star Luke Baybak Tony Guest Star Brendan Michael Coughlin Mickey Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer David Platt Director David Foster Writer