Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Anne Dudek Dr. Amber Volakis Guest Star Edi Gathegi Dr. Jeffrey 'Big Love' Cole Guest Star Peter Jacobson Dr. Chris Taub Guest Star Kal Penn Dr. Lawrence Kutner Guest Star Olivia Wilde Thirteen, Dr. Remy Hadley Guest Star Steve Valentine Flynn Guest Star Noelle Drake Ilana Guest Star Joe Ochman Surgeon Guest Star Mandy McMillian Nurse 1 Guest Star Adria Johnson Nurse 2 Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Lesli Linka Glatter Director Sara Hess Writer