Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Jon Seda Donny Guest Star Alexandra Barreto Cheryl Guest Star Samuel Carman Michael Guest Star Jack Impellizzeri Brian Guest Star Richard King Boutain Guest Star Briana Venskus Nona Guest Star Marcus Toji Dex Guest Star Samantha Colburn Marta Guest Star Sanjay Madhav Singh Guest Star Taira Soo Anne Ayala Guest Star Doug McKeon Priest Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Matt Shakman Director Lawrence Kaplow Writer