Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Robert Sean Leonard Dr. James Wilson Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Olivia Wilde Thirteen, Dr. Remy Hadley Actor Amber Tamblyn Martha M. Masters Guest Star Cynthia Watros Sam Carr Guest Star Jennifer Crystal Foley Rachel Taub Guest Star Candice Bergen Arlene Cuddy Guest Star Bobbin Bergstrom Nurse Guest Star Paula Marshall Julia Cuddy Guest Star Kayla Colbert Rachel Cuddy Guest Star Zena Grey Ruby Guest Star Rylie Colbert Rachel Cuddy Guest Star Kayla Ewell Nika Guest Star Helena Lewis Nurse Ellen Hoffner Guest Star Nigel Gibbs Sanford Wells Guest Star Liz Benoit Nurse Anne Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Greg Yaitanes Director Miguel Sapochnik Director David Straiton Director Sanford Bookstaver Director Tucker Gates Director Peter Blake Writer John C. Kelley Writer Seth Hoffman Writer Thomas L. Moran Writer Liz Friedman Writer Eli Attie Writer David Foster Writer Kath Lingenfelter Writer David Hoselton Writer Lawrence Kaplow Writer Sara Hess Writer