Hugh Laurie Dr. Gregory House Actor Robert Sean Leonard Dr. James Wilson Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Odette Annable Dr. Jessica Adams Actor Charlyne Yi Dr. Chi Park Actor Thom Barry Dr. Sykes Guest Star Kaleti Williams Asofa Guest Star Sebastian Sozzi Nick Guest Star Michael Massee Frankie Guest Star Jude Ciccolella Mendelson Guest Star Michael Bailey Smith Sullivan Guest Star Jaleel White Porter Guest Star Nate Mooney Rollo Guest Star Mars Crain Stomper Guest Star Wayne Lopez C.O. Alvarez Guest Star Jeannine Cota C.O. Hsueh Guest Star Robbie Kaller Garcia Guest Star Damon Christopher Nick's Cellmate Guest Star Michael Paré Warden Delaire Guest Star Pamela Shaddock Case Worker Guest Star Bianca DeGroat Nurse Kathy Hostetter Guest Star Michael C. Monroe Turner Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Greg Yaitanes Director Peter Blake Writer