Damon Wayans Roger Murtaugh Actor Clayne Crawford Martin Riggs Actor, Director Kevin Rahm Captain Brooks Avery Actor Jordana Brewster Dr. Maureen "Mo" Cahill Actor Keesha Sharp Trish Murtaugh Actor Johnathan Fernandez Scorsese Actor Michelle Mitchenor Detective Bailey Actor Dante Brown Roger Murtaugh Jr. Actor Chandler Kinney Riana Murtaugh Actor Monica Barbaro Nora Guest Star Adrian Pasdar Cooper Guest Star Rex Linn Nathan Riggs Guest Star Andrew Creer Zach Bowman Guest Star Matt Miller Executive Producer McG Executive Producer Dan Lin Executive Producer Jennifer Gwartz Executive Producer Steve Boyum Director Omar Madha Director Eric Laneuville Director Salli Richardson-Whitfield Director Maja Vrvilo Director John Behring Director Larry Teng Director Silver Tree Director Nick Copus Director