Dianne Wiest Joan Actor James Brolin John Actor Zoe Lister Jones Jen Actor Colin Hanks Greg Actor Angelique Cabral Colleen Actor Thomas Sadoski Matt Actor Betsy Brandt Heather Actor Dan Bakkedahl Tim Actor Niall Cunningham Tyler Actor Holly J. Barrett Samantha Actor Giselle Eisenberg Sophia Actor Hunter King Clementine Actor Russell Peters Dr. Tak Oh Guest Star Martin Mull Gary Timpkins Guest Star Pam Trotter Pam Guest Star Lucas Hazlett Griff Guest Star Jonathan Marballi Levi Guest Star Carla Renata Physician's Assistant Guest Star Michael Strassner Head Wound Guy Guest Star Mo Welch Barista Guest Star Justin Adler Executive Producer Aaron Kaplan Executive Producer Jason Winer Executive Producer Jeffrey Morton Executive Producer Brad Copeland Writer, Executive Producer Alisa Statman Director