Ryan Eggold Dr. Max Goodwin Actor Freema Agyeman Dr. Helen Sharpe Actor Janet Montgomery Dr. Lauren Bloom Actor Jocko Sims Dr. Floyd Reynolds Actor Tyler Labine Dr. Iggy Frome Actor Anupam Kher Dr. Vijay Kapoor Actor Daniel Dae Kim Dr. Cassian Shin Guest Star Mike Doyle Martin McIntyre Guest Star Larae Muscat Sameera Guest Star Vince Edgehill Dying Patient Guest Star Em Grosland ED Nurse Brunstetter Guest Star Christine Chang Dr. Agnes Kao Guest Star Alejandro Hernández ED Nurse Casey Acosta Guest Star Michael Basile Paramedic Moreland Guest Star Erica Camarano Trauma Surgeon Reyes Guest Star Matthew Jeffers ED Resident Mark Walsh Guest Star Stacey Raymond Paramedic Whitaker Guest Star Teresa Patel Paramedic Harvell Guest Star Melissa Navia Copilot Eva Schafer Guest Star Raphael Sbarge Captain Dane Starks Guest Star Olivia Khoshatefeh Anesthesiologist Alicia Smith Guest Star Maury Ginsberg Dr. Leland Clark Guest Star Sheilagh Weymouth Dr. Florence Brighton Guest Star Megan Byrne Gladys Guest Star Keren Lugo Dr. Diana Flores Guest Star Namakula DOJ Agent Southern Guest Star Jennifer Betit Yen Nurse Aimee Kamoe Guest Star Carmen Noemi Guzman Wife of Dying Patient Guest Star Shereen Ahmed Shenaz Shetty Guest Star Jay Fernandez NTSB Nelson Peña Guest Star Earl Baker Jr. Dr. Mandle Guest Star Stephen Hu Dr. William "Bill" Choi Guest Star Elena Araoz Dr. Miriam Kamnani Guest Star Nora Clow Luna Guest Star Opal Clow Luna Guest Star David Schulner Executive Producer, Writer Peter Horton Executive Producer, Director Michael Slovis Executive Producer David Foster Executive Producer Aaron Ginsburg Executive Producer Shaun Cassidy Executive Producer