Evan Dunsky Creator, Executive Producer Liz Brixius Creator, Executive Producer Linda Wallem Creator, Executive Producer Edie Falco Jackie Peyton Actor Eve Best Dr. O'Hara Actor Peter Facinelli Dr. Cooper Actor Merritt Wever Zoey Actor Paul Schulze Eddie Actor Anna Deavere Smith Gloria Akalitus Actor Dominic Fumusa Kevin Peyton Actor Ruby Jerins Grace Peyton Actor Mackenzie Aladjem Fiona Peyton Actor Stephen Wallem Thor Lundgren Actor Arjun Gupta Sam Guest Star Michael Buscemi God Guest Star Deidre Goodwin Brooke Guest Star Pedro Pascal Steve Guest Star Jolly Abraham CF Lab Tech Guest Star Paul Feig Director Mark Hudis Writer, Executive Producer Richie Jackson Executive Producer Caryn Mandabach Executive Producer Christine Zander Executive Producer