Chad Michael Murray Lucas Scott Actor James Lafferty Nathan Scott Actor Hilarie Burton Peyton Sawyer Actor Bethany Joy Lenz Haley James Scott Actor Paul Johansson Dan Scott Actor Sophia Bush Brooke Davis Actor Barbara Alyn Woods Deb Scott Actor Barry Corbin Coach Brian "Whitey" Durham Actor Craig Sheffer Keith Scott Actor Moira Kelly Karen Roe Actor Micahel Copon Guest Star Kieren Hutchison Guest Star Lee Norris Guest Star Vaughn Wilson Guest Star Ashley Novasad Guest Star Mark Schwahn Executive Producer Michael Tollin Executive Producer Brian Robbins Executive Producer Joe Davola Executive Producer Joanna Kerns Director Jennifer Cecil Writer