Chad Michael Murray Lucas Scott Actor James Lafferty Nathan Scott Actor Hilarie Burton Peyton Sawyer Actor Bethany Joy Lenz Haley James Scott Actor Paul Johansson Dan Scott Actor Sophia Bush Brooke Davis Actor Barbara Alyn Woods Deb Scott Actor Barry Corbin Coach Brian "Whitey" Durham Actor Craig Sheffer Keith Scott Actor Moira Kelly Karen Roe Actor Michael Copon Felix Taggarro Guest Star Daniella Alonso Anna Taggarro Guest Star Maria Menounos Jules Guest Star Tyler Hilton Chris Keller Guest Star Kieren Hutchison Andy Hargrove Guest Star Sarah Edwards Theresa Actor Lee Norris Mouth Actor Cullen Moss Junk Actor Mark Schwahn Executive Producer Michael Tollin Executive Producer Brian Robbins Executive Producer Joe Davola Executive Producer David Paymer Director R. Lee Flemming Jr. Writer