Chad Michael Murray Lucas Scott Actor James Lafferty Nathan Scott Actor Hilarie Burton Peyton Sawyer Actor Bethany Joy Lenz Haley James Scott Actor Paul Johansson Dan Scott Actor Sophia Bush Brooke Davis Actor Barbara Alyn Woods Deb Scott Actor Barry Corbin Coach Brian "Whitey" Durham Actor Craig Sheffer Keith Scott Actor Moira Kelly Karen Roe Actor Maria Menounos Guest Star Tyler Hilton Guest Star Kieren Hutchison Guest Star Nick Zano Guest Star Bryan Greenberg Guest Star Mark Schwahn Executive Producer Michael Tollin Executive Producer Brian Robbins Executive Producer Joe Davola Executive Producer Stacy Rukeyser Writer Billy Dickson Director