Chad Michael Murray Lucas Scott Actor James Lafferty Nathan Scott Actor Hilarie Burton Peyton Sawyer Actor Bethany Joy Lenz Haley James Scott , Haley James Actor Paul Johansson Dan Scott Actor Sophia Bush Brooke Davis Actor Barbara Alyn Woods Deb Scott , Deb Lee Actor Barry Corbin Coach Brian "Whitey" Durham Actor Craig Sheffer Keith Scott Actor Moira Kelly Karen Roe , Karen Scott Actor Lee Norris Guest Star Antwon Tanner Guest Star Brett Claywell Guest Star Vaughn Wilson Guest Star Cullen Moss Guest Star Mark Schwahn Executive Producer Michael Tollin Executive Producer Brian Robbins Executive Producer Joe Davola Executive Producer Les Butler Director Mark B. Perry Writer