Chad Michael Murray Lucas Scott Actor James Lafferty Nathan Scott Actor Hilarie Burton Peyton Sawyer Actor Bethany Joy Lenz Haley James-Scott Actor Paul Johansson Dan Scott Actor Sophia Bush Brooke Davis Actor Barbara Alyn Woods Deb Scott Guest Star Lee Norris Mouth McFadden Guest Star Antwon Tanner Antwon 'Skills' Taylor Actor Danneel Ackles Rachel Gatina Actor Barry Corbin Coach Brian "Whitey" Durham Actor Moira Kelly Karen Roe Actor Matt Barr Derek Guest Star Elisabeth Harnois Guest Star Lupe Fiasco Self Guest Star Mark Schwahn Executive Producer Michael Tollin Executive Producer Brian Robbins Executive Producer Joe Davola Executive Producer Bethany Rooney Director Terrence Coli Writer