James Lafferty Nathan Scott Actor Bethany Joy Lenz Haley James-Scott Actor Sophia Bush Brooke Davis Actor, Director Austin Nichols Julian Baker Actor Robert Buckley Clay Evans Actor Shantel VanSanten Quinn James Actor Jackson Brundage Jamie Scott Actor Lee Norris Marvin 'Mouth' McFadden Actor Jana Kramer Alex Dupré Actor Lisa Goldstein Millicent 'Millie' Huxtable Actor Sharon Lawrence Guest Star Stephen Colletti Guest Star Kate Voegele Guest Star Amanda Schull Guest Star Laura Izibor Guest Star Mark Schwahn Executive Producer Joe Davola Executive Producer Gregory Prange Executive Producer Michael Tollin Executive Producer Brian Robbins Executive Producer John Norris Writer