Benedict Cumberbatch Patrick Melrose Actor, Executive Producer Dainton Anderson Thomas Melrose Actor Holliday Grainger Bridget Watson Scott Actor Jessica Raine Julia Actor Blythe Danner Nancy Actor Celia Imrie Kettle Actor Hugo Weaving David Melrose Actor Harriet Walter Princess Margaret Actor Pip Torrens Nicholas Pratt Actor Anthony Boyle Barry Actor Prasanna Puwanarajah Johnny Hall Actor Anna Madeley Mary Actor Indira Varma Anne Moore Actor Richard Brake Mark Actor Annabel Mullion Annabel Actor Marcus Smith Robert Melrose Actor Nancy Crane Nancy Banks Actor Cameron Jack Terry Actor Sebastian Maltz Young Patrick Melrose Actor Eben Young Jerry Banks Actor Edward Berger Director David Nicholls Writer Edward St. Aubyn Writer Volker Bertelmann Music Stephen Smallwood Producer Rachael Horovitz Executive Producer Michael Jackson Executive Producer Adam Ackland Executive Producer Helen Flint Executive Producer