Matthew Rhys Perry Mason Actor Tatiana Maslany Sister Alice Actor John Lithgow Elias Birchard "E.B." Jonathan Actor Chris Chalk Paul Drake Actor Shea Whigham Pete Strickland Actor Juliet Rylance Della Street Actor Gayle Rankin Emily Dodson Actor Verónica Falcón Lupe Gibbs Actor Robert Patrick Herman Baggerly Actor Jefferson Mays Virgil Sheets Actor Eric Lange Detective Holcomb Actor Andrew Howard Detective Ennis Actor Nathan Corddry Matthew Dodson Actor Hemky Madera Rigoberto Actor Matt Malloy Frank Dillon Actor Aaron Stanford George "Pinky Ring" Gannon Actor Charles Baker Stanislaw Nowak Actor Madeline Zima Velma "Red" Fuller Actor Matt Lasky Marcin Sarecki aka Black Hat Actor Mike O'Gorman Walt LeBaron Actor Tim Ransom Fenton Bostwick Actor Gretchen Mol Linda Voice