James Roday Rodriguez Shawn Spencer Actor Dulé Hill Burton "Gus" Guster Actor Corbin Bernsen Henry Spencer Actor Timothy Omundson Detective Carlton Lassiter Actor Kirsten Nelson Police Chief Karen Vick Actor Maggie Lawson Detective Juliet O'Hara Actor Kurt Fuller Woody Guest Star Michael Weston Guest Star Ray Wise Guest Star Alan Ruck Guest Star Janet Varney Guest Star Dana Ashbrook Guest Star Lindsay Sloane Guest Star Ralph Macchio Guest Star Ed Lover Guest Star Carlos Jacott Guest Star Katharine Isabelle Guest Star Steve Franks Executive Producer Kelly Kulchak Executive Producer Chris Henze Executive Producer Bill Callahan Executive Producer