Emma Roberts Chanel Oberlin Actor Jamie Lee Curtis Dean Cathy Munsch Actor Lea Michele Hester Actor Abigail Breslin Chanel No. 5 Actor Billie Lourd Chanel No. 3 Actor Keke Palmer Zayday Williams Actor John Stamos Dr. Brock Holt Actor Taylor Lautner Dr. Cassidy Cascade Actor James Earl Chamberlain Jackson Actor Niecy Nash Guest Star Cecily Strong Guest Star Jerry O'Connell Guest Star Laura Bell Bundy Guest Star Jeremy Batiste Guest Star Trilby Glover Guest Star Ryan Murphy Executive Producer Brad Falchuk Executive Producer Ian Brennan Executive Producer Alexis Martin Woodall Executive Producer