Tom Welling Clark Kent Actor Kristin Kreuk Lana Lang Actor Michael Rosenbaum Lex Luthor Actor Allison Mack Chloe Sullivan Actor John Schneider Jonathan Kent Actor Annette O'Toole Martha Kent Actor John Glover Lionel Luthor Actor Erica Durance Lois Lane Actor James Marsters Milton Fine Guest Star Nichole Hiltz Simone Charcot Guest Star Linden Banks Scientist Guest Star Aaron Craven Scientist Guest Star Alejandro Chavarria Honduran Boy Guest Star Alfred Gough Executive Producer Miles Millar Executive Producer Mike Rohl Director Todd Slavkin Writer Darren Swimmer Writer