Johnny Galecki Leonard Hofstadter Actor Jim Parsons Sheldon Cooper Actor Kaley Cuoco Penny Actor Simon Helberg Howard Wolowitz Actor Kunal Nayyar Raj Koothrappali Actor Mayim Bialik Amy Farrah Fowler Actor Melissa Rauch Bernadette Rostenkowski Actor Brian George Dr. V.M. Koothrappali Guest Star Alice Amter Mrs. Koothrappali Guest Star Katie Leclerc Emily Guest Star Chuck Lorre Executive Producer, Writer Bill Prady Executive Producer, Writer David Goetsch Writer Anthony Del Broccolo Writer Steven Molaro Writer Steve Holland Writer Mark Cendrowski Director