Dan Castellaneta Homer Jay Simpson, Barney Gumble, Grampa Simpson, Mayor Joe Quimby, Krusty the Klown, Groundskeeper Willie Voice Julie Kavner Marjorie Bouvier Simpson, Patty Bouvier, Selma Bouvier, Grandma Jackie Bouvier Voice Nancy Cartwright Bartholomew Jo-Jo "Bart" Simpson, Nelson Muntz Voice Yeardley Smith Lisa Marie Simpson Voice Harry Shearer Charles Montgomery Burns, Waylon Smithers, Principal Seymour Skinner, Ned Flanders, Otto Mann, Scratchy, Kent Brockman, Dr. Julius Hibbert, Reverend Timothy Lovejoy Voice Hank Azaria Moe Szyslak, Apu Nahasapeemapetilon, Chief Clancy Wiggum, Dr. Nick Riviera Voice Jon Lovitz Jay Sherman Guest Voice Phil Hartman Charlton Heston Guest Voice Maurice LaMarche Eudora Welty , George C. Scott Guest Voice Doris Grau Various Guest Voice Pamela Hayden Milhouse Van Houten Guest Voice Maggie Roswell Maude Flanders Guest Voice James L. Brooks Executive Producer Matt Groening Executive Producer David Mirkin Executive Producer