Dan Castellaneta Homer Jay Simpson, Barney Gumble, Grampa Simpson, Mayor Joe Quimby, Krusty the Klown, Groundskeeper Willie Voice Julie Kavner Marjorie Bouvier Simpson, Patty Bouvier, Selma Bouvier, Grandma Jackie Bouvier Voice Nancy Cartwright Bartholomew Jo-Jo "Bart" Simpson, Nelson Muntz Voice Yeardley Smith Lisa Marie Simpson Voice Hank Azaria Moe Szyslak, Apu Nahasapeemapetilon, Chief Clancy Wiggum, Dr. Nick Riviera Voice Harry Shearer Charles Montgomery Burns, Waylon Smithers, Principal Seymour Skinner, Ned Flanders, Otto Mann, Scratchy, Kent Brockman, Dr. Julius Hibbert, Reverend Timothy Lovejoy Voice Pamela Hayden Milhouse Van Houten Voice Tress MacNeille Dolph Voice Judd Apatow Himself Guest Voice Leslie Mann Herself Guest Voice Paul Rudd Paul Rudd , Judd Apatow Guest Voice Seth Rogen Himself Guest Voice Channing Tatum Himself Guest Voice Rob Halford Himself Guest Voice Will Arnett Deputy Director Gratman Guest Voice Chris Edgerly Additional Voices Guest Voice James L. Brooks Executive Producer Matt Groening Executive Producer Al Jean Executive Producer Matthew Nastuk Director