Morris Chestnut Dr. John Watson Actor, Executive Producer Eve Harlow Dr. Ingrid Derian Actor Peter Mark Kendall Dr. Stephens Croft, Dr. Adam Croft Actor Ritchie Coster Shinwell Johnson Actor Inga Schlingmann Dr. Sasha Lubbock Actor Rochelle Aytes Dr. Mary Morstan Actor Robert Carlyle Sherlock Holmes Guest Star Noah Mills Beck Wythe Guest Star Clarke Peters Hamish Watson Guest Star Shannon Purser Guest Star Nat Faxon Hobie McSorley Guest Star Johnno Wilson Joseph Bell Actor Tika Sumpter Laila Guest Star Vincent Gale Mycroft Holmes Actor Carlena Britch Ria Actor Jamall Johnson Ranger Actor Cindy Piper Ruth Actor Craig Sweeny Executive Producer, Writer Aaron Kaplan Executive Producer Larry Teng Executive Producer, Director Brian Morewitz Executive Producer Shäron Moalem Executive Producer Sallie Patrick Executive Producer Charly Evon Simpson Writer Anna Mackey Writer Elizabeth Klaviter Writer Sharde Miller Writer Michael Narducci Writer Teresa Tuan Writer Sheelin Choksey Director Jason Inman Writer Amanda Row Director Guy Ferland Director Jeff Byrd Director