David Kohan Creator, Executive Producer Max Mutchnick Creator, Executive Producer Eric McCormack Will Truman Actor Debra Messing Grace Adler Actor Sean Hayes Jack McFarland Actor Megan Mullally Karen Walker Actor Debbie Reynolds Bobbi Adler Guest Star Lainie Kazan Aunt Honey Guest Star Beau Bridges Daniel McFarland Guest Star Michael Angarano Elliot Guest Star Kenneth Mars Uncle Sid Guest Star Helen Slater Peggy Truman Guest Star Nick Offerman Nick Guest Star Clinton Leupp Lawrence Guest Star Murray Gershenz Uncle Funny Guest Star Gene Elman Uncle Winnie Guest Star James Burrows Executive Producer, Director Jeff Greenstein Executive Producer Bruce Alden Producer Peter Chakos Producer Kari Lizer Writer