David Kohan Creator, Executive Producer Max Mutchnick Creator, Executive Producer Eric McCormack Will Truman Actor Debra Messing Grace Adler Actor Sean Hayes Jack McFarland Actor Megan Mullally Karen Walker Actor Shelley Morrison Rosario Salazar Actor Demi Moore Sissy Palmer-Ginsburg Guest Star Leigh-Allyn Baker Ellen Guest Star Rosanna Arquette Julie Guest Star James Burrows Executive Producer, Director Jeff Greenstein Executive Producer Laura Kightlinger Writer Alex Herschlag Executive Producer Jhoni Marchinko Executive Producer