David Kohan Creator, Executive Producer Max Mutchnick Creator, Executive Producer Eric McCormack Will Truman Actor Debra Messing Grace Adler Actor Sean Hayes Jack McFarland Actor Megan Mullally Karen Walker Actor Edward Burns Nick Guest Star Alec Baldwin Malcolm Widmark Guest Star Blythe Danner Marilyn Truman Guest Star Molly Shannon Val Bassett Guest Star Erinn Hayes Katherine Fallon Guest Star Shelley Morrison Rosario Salazar Guest Star Bobby Cannavale Vince D'Angelo Guest Star Jeff Goldblum Scott Woolley Guest Star Eric Stoltz Tom Cassidy Guest Star Jamie-Lynn Sigler Ro Guest Star Karl T. Wright Wayne Guest Star Will Arnett Artemus Johnson Guest Star Paola Presta Mark Guest Star Debbie Reynolds Bobbi Adler Guest Star Chita Rivera Lenore Guest Star Charles C. Stevenson Jr. Smitty Guest Star James Burrows Executive Producer, Director Alex Herschlag Executive Producer, Writer David Flebotte Executive Producer Kate Angelo Writer Gail Lerner Writer Gary Janetti Writer Tracy Poust Writer Sally Bradford Writer Bill Wrubel Writer Greg Malins Writer Kirk J. Rudell Writer Steve Gabriel Writer Jordana Arkin Writer Jon Kinnally Writer