Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Ryan Phuong Tam Guest Star Valerie Mahaffey Ms. Macelroy Guest Star Rex Linn Principal Petersen Guest Star Danielle Pinnock Ms. Ingram Guest Star Doc Farrow Coach Wilkins Guest Star Frances Conroy Flora Guest Star Harry Groener Elliot Guest Star Chuck Lorre Executive Producer, Writer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Rob Ulin Writer David Bickel Writer Rebecca Asher Director