Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Wallace Shawn Dr. John Sturgis Guest Star Barry Corbin Mr. Gilford Guest Star Matt Hobby Pastor Jeff Guest Star Danielle Pinnock Ms. Ingram Guest Star Sarah Baker Ms. Hutchins Guest Star Nancy Linehan Charles Peg Guest Star Bryce McBratnie Elliot Guest Star Megan Park Francine Guest Star John Eddins Paramedic Guest Star Parker Dailey Five-Year-Old Sheldon Guest Star Chuck Lorre Executive Producer, Writer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Tara Hernandez Writer Jeremy Howe Writer Connor Kilpatrick Writer Jaffar Mahmood Director