Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Wallace Shawn Dr. John Sturgis Guest Star Ed Begley Jr. Dr. Linkletter Guest Star Ryan Phuong Tam Guest Star Doc Farrow Assistant Coach Wilkins Guest Star Chuck Lorre Executive Producer, Writer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Damir Konjicija Writer Dario Konjicija Writer Eric Kaplan Writer Tara Hernandez Writer Jaffar Mahmood Director