Spike Lee Mookie Director, Actor, Screenwriter, Producer Clarke Peters Enoch Actor Jules Brown Flik Actor Toni Lysaith Chazz Actor Nate Parker Box Actor Thomas Jefferson Byrd Deacon Zee Actor Heather Simms Sister Sharon Actor Colman Domingo Blessing Rowe Actor James Ransone Kevin Actor De'Adre Aziza Colleen Royale Actor Kimberly Hebert Gregory Sister Sweet Actor Stephen Henderson Deacon Yancy Actor Jon Batiste Da Organist TK Hazelton Actor Isiah Whitlock Jr. Det. Flood Actor James McBride Screenwriter Kerwin DeVonish Cinematographer Hye Mee Na Film Editing Bruce Hornsby Original Music Judith Hill Original Songs Sarah Frank Production Design Sila Karakaya Art Director Tiisetso Dladla Art Director Emilio Sosa Costume Design Speeezzy Leeezzzy Casting