George C. Wolfe Director, Screenwriter Oprah Winfrey Deborah Lacks Actor, Executive Producer Rose Byrne Rebecca Skloot Actor Renée Elise Goldsberry Henrietta Lacks Actor Rocky Carroll Sonny Lacks Actor Courtney B. Vance Sir Lord Keenan Kester Cofield Actor Reg E. Cathey Zakariyya Actor Reed Birney Dr. George Gey Actor Leslie Uggams Sadie Actor John Benjamin Hickey Bill Watson Actor Ruben Santiago-Hudson Dr. Pattillo Actor Byron Jennings Dr. Victor McKusick Actor John Douglas Thompson Lawrence Actor Roger Robinson Day Lacks Actor Adriane Lenox Barbara Actor Gabriel Ebert Dr. Christoph Lengauer Actor Peter Gerety Paul Lurz Actor John Beasley Cliff Actor Kyanna Simone Simpson Young Deborah Lacks Actor Peter Landesman Screenwriter Alexander Woo Screenwriter Alan Ball Executive Producer Peter Macdissi Executive Producer Carla Gardini Executive Producer Lydia Dean Pilcher Executive Producer