Zachary Quinto Dr. Oliver Thredson Actor Joseph Fiennes Monsignor Timothy Howard Actor Sarah Paulson Lana Winters Actor Evan Peters Kit Walker Actor Lily Rabe Sister Mary Eunice Actor Lizzie Brocheré Grace Actor James Cromwell Dr. Arthur Arden Actor Jessica Lange Sister Jude Actor Chloë Sevigny Shelley Guest Star Fredric Lehne Frank McCann Guest Star Britne Oldford Alma Walker Guest Star Joe Egender Billy Guest Star Barbara Tarbuck Mother Superior Claudia Guest Star Matthew John Armstrong Detective Byers Guest Star Joel McKinnon Miller Detective Connors Guest Star Franka Potente Anne Frank Guest Star John Lee Ames Rudy Guest Star John Cromwell Young Arden Guest Star Bella Dayne Patsy Guest Star Kathrine Herzer Young Anne Frank Guest Star Joe Howard Speaker Guest Star Kelly Schumann Azalea Guest Star Casey Wyman Daniel Guest Star Ryan Murphy Executive Producer Brad Falchuk Executive Producer Dante Di Loreto Executive Producer Tim Minear Executive Producer