Zachary Quinto Dr. Oliver Thredson Actor Joseph Fiennes Monsignor Timothy Howard Actor Sarah Paulson Lana Winters Actor Evan Peters Kit Walker Actor Lily Rabe Sister Mary Eunice Actor Lizzie Brocheré Grace Actor James Cromwell Dr. Arthur Arden Actor Jessica Lange Sister Jude Actor Chloë Sevigny Shelley Guest Star Fredric Lehne Frank McCann Guest Star Britne Oldford Alma Walker Guest Star Mark Margolis Sam Goodman Guest Star David Chisum Jim Brown Guest Star Matthew John Armstrong Detective Byers Guest Star Joel McKinnon Miller Detective Connors Guest Star Franka Potente Anne Frank , Charlotte Brown Guest Star Valorie Hubbard Mrs. Hindsman Guest Star Abby Donnelly Peggy Cartwright Guest Star Ted Mattison Stranger Guest Star Ryan Murphy Executive Producer Brad Falchuk Executive Producer Dante Di Loreto Executive Producer Tim Minear Executive Producer