Marcia Gay Harden Dr. Leanne Rorish Actor Boris Kodjoe Dr. Will Campbell Actor Melanie Chandra Dr. Malaya Pineda Actor Harry Ford Dr. Angus Leighton Actor Benjamin Hollingsworth Dr. Mario Savetti Actor Jillian Murray Dr. Heather Pinkney Actor William Allen Young Dr. Rollie Guthrie Actor Luis Guzmán Jesse Sallander Actor Rob Lowe Col. Ethan Willis Actor Tommy Dewey Mike Leighton Guest Star Noah Gray-Cabey Dr. Elliot Dixon Guest Star Emily Tyra Dr. Noa Kean Guest Star Nafessa Williams Dr. Charlotte Piel Guest Star Angela Relucio Risa Park Guest Star Emily Nelson Hannah Reynolds Guest Star Steven Culp Desmond Leighton Guest Star George Lako Flight Medic 1 Guest Star Brandon Lynch Flight Medic 2 Guest Star Emma Engle Kaya Guest Star Madalyn Horcher Jaydin Guest Star Nefe Iredia EMT Guest Star Robert Romanus Henry Underwood Guest Star Mike Erwin Randall Underwood Guest Star Bianca Collins Chelsea Underwood Guest Star Julie Ann Emery Debbie Kobling Guest Star Angela Fornero Post-Op Nurse Guest Star Kristina Guerrero Field Reporter Guest Star Michael Seitzman Executive Producer, Writer David Semel Executive Producer Ryan McGarry Executive Producer Marti Noxon Executive Producer Linda Goldstein Knowlton Executive Producer Loni Peristere Director