Forest Whitaker Special Agent Sam Cooper Actor Janeane Garofalo Beth Griffith Actor Michael Kelly John "Prophet" Sims Actor Beau Garrett Gina LaSalle Actor Matt Ryan Mick Rawson Actor Kirsten Vangsness Penelope Garcia Actor J.D. Walsh Kelvin Cornwell Guest Star Zoey Deutch Blue Mask Girl Guest Star Billy Gallo Billy Gallo Guest Star Laura Spencer Sophia Guest Star Owen Martin Tom Guest Star Alain Uy Medical Examiner Guest Star Jason Connery John Clayford Guest Star Eden Malyn Cindy Shearin Guest Star Charline St. Charles Surgical Nurse Guest Star Chuck McCollum Dr. Elderman Guest Star Christine Garver Dawn Taggert Guest Star Cooper Huckabee Emory Boyd Guest Star Jodi Carlisle Helen Holton Guest Star Henderson Wade Officer Dentler Guest Star Chris Mundy Executive Producer Edward Allen Bernero Executive Producer Mark Gordon Executive Producer Deborah Spera Executive Producer Felix Alcala Director Mark Richard Writer