Gary Sinise Det. Mack "Mac" Taylor Actor Sela Ward Jo Danville Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Eddie Cahill Det. Donald Flack, Jr. Actor Anna Belknap Det. Lindsay Monroe Messer Actor A.J. Buckley Adam Ross Actor Robert Joy Dr. Sid Hammerback Actor Peter Fonda William Hunt Guest Star Clifton Collins Jr. Raymond Harris Guest Star Jenny Mollen Detective Angela Sayer Guest Star Vince Pavia Officer Stone Guest Star Michael Worth Guest Star Alana Morshead Guest Star Sheridan Crist Trevor Arnette Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer Christopher Silber Writer Adam Targum Writer Jeffrey Hunt Director