Gary Sinise Det. Mack "Mac" Taylor Actor Sela Ward Jo Danville Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Eddie Cahill Det. Donald Flack, Jr. Actor Anna Belknap Det. Lindsay Monroe Messer Actor A.J. Buckley Adam Ross Actor Robert Joy Dr. Sid Hammerback Actor Natalie Martinez Detective Jamie Lovato Guest Star Rob Morrow Leonard Brooks Guest Star Victoria Hoffman Guest Star Laura Parker Jennifer Brooks Guest Star Cara Pifko Rachel Moore Guest Star David Bloom Young Leonard Brooks Guest Star Brace Harris Uni Guest Star Napoleon Tavale ESU Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer Adam Targum Writer Sarah Byrd Writer Skip Sudduth Director