David S. Goyer Creator, Executive Producer Tom Riley Leonardo da Vinci Actor Laura Haddock Lucrezia Donati Actor Elliot Cowan Lorenzo Medici Actor Lara Pulver Clarice Orsini Actor Blake Ritson Count Girolamo Riario Actor Gregg Chillin Zoroaster Actor Hera Hilmar Vanessa Actor Eros Vlahos Nico Actor James Faulkner Pope Sixtus IV Actor Carolina Guerra Ima Actor Kieran Bew Duke Alfonso Actor Julie Gardner Executive Producer Jane Tranter Executive Producer