Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor John Noble Mr. Morland Holmes Actor Samantha Quan Guest Star Christina Cox Guest Star Jason Dirden Guest Star Evan Hall Guest Star Margo Seibert Guest Star Luna Lauren Velez Guest Star Quentin Mare Guest Star Tijuana Ricks Guest Star Lauren Culpepper Guest Star Andy Lucien Guest Star Victoria Janicki Guest Star Zanny Laird Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer John Polson Executive Producer Jason Tracey Executive Producer Arika Lisanne Mittman Writer Ron Fortunato Director