Goran Visnjic Dr. Luka Kovac Actor Maura Tierney Abby Lockhart Actor Mekhi Phifer Dr. Gregory Pratt Actor Parminder Nagra Dr. Neela Rasgotra Actor Linda Cardellini Nurse Samantha Taggart Actor Shane West Actor Scott Grimes Dr. Archie Morris Actor Laura Innes Dr. Kerry Weaver Actor John Stamos Dr. Tony Gates Actor Stanley Tucci Dr. Kevin Moretti Guest Star Sam Jones III Chaz Pratt Guest Star Gina Ravera Dr. Bettina DeJesus Guest Star Malaya Rivera Drew Katey Alvaro Guest Star Jesse Borrego Javier Guest Star Laura Cerón Nurse Chuny Marquez Guest Star Troy Evans Frank Martin Guest Star Gil McKinney Dr. Paul Grady Guest Star Natacha Roi Serena Lipnicki Guest Star Miles Heizer Joshua Lipnicki Guest Star Christopher Chulack Executive Producer Michael Crichton Executive Producer David Zabel Executive Producer John Wells Executive Producer R. Scott Gemmill Executive Producer