Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Isaiah Washington Dr. Preston Burke Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor T.R. Knight Dr. George O'Malley Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Kate Walsh Dr. Addison Montgomery Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Diahann Carroll Guest Star Loretta Devine Guest Star Elizabeth Reaser Guest Star Jason London Guest Star Chyler Leigh Guest Star Steven W. Bailey Guest Star Tsai Chin Guest Star Aasha Davis Guest Star Kevin Rankin Guest Star Brian Tee Guest Star Jack Yang Guest Star Derek Phillips Guest Star Robin Pearson Rose Guest Star Ajay Vidure Guest Star Candice Afia Guest Star Artie O'Daly Guest Star Joseph Williamson Guest Star Traber Burns Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Tony Phelan Writer Joan Rater Writer Rob Corn Director