Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor T.R. Knight Dr. George O'Malley Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Chyler Leigh Dr. Lexie Grey Actor Ben Vereen Guest Star Brennan Elliott Guest Star Nicholas Gonzalez Guest Star Diahann Carroll Guest Star Amy Landers Guest Star Tanya Linette Smith Guest Star Moe Irvin Guest Star Brooke Blanchard Guest Star Ray Ford Guest Star Candice Afia Guest Star Amrapali Ambegaokar Guest Star Mark Saul Guest Star Joseph Williamson Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Debora Cahn Writer James Frawley Director