Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor T.R. Knight Dr. George O'Malley Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Chyler Leigh Dr. Lexie Grey Actor Brooke Smith Dr. Erica Hahn Actor Edward Herrmann Guest Star Elizabeth Reaser Guest Star Rocky Carroll Guest Star Kali Rocha Guest Star David Clennon Guest Star Dylan Minnette Guest Star Sarah Utterback Guest Star Anjul Nigam Guest Star Bhama Roget Guest Star Crystal Kwon Guest Star Jeremiah Hu Guest Star Ray Ford Guest Star Linda Eve Miller Guest Star Suzanne Quinn Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Krista Vernoff Writer Bethany Rooney Director