James Arness Marshal Matt Dillion Actor Milburn Stone Dr. Galen "Doc" Adams Actor Amanda Blake Kitty Russell Actor Ken Curtis Festus Guest Star Ted Jordan Nathan Burke Guest Star Glenn Strange Sam Noonan Guest Star James Stacy Bob Johnson Guest Star Chill Wills Red Conniston Guest Star Edmund Hashim Monk Wiley Guest Star Gene Evans Clint Sorils Guest Star James Anderson Hiller Guest Star Norman Alden Purlie Loftus Guest Star Buck Taylor Leonard Praker Guest Star Dan Ferrone Honker Guest Star Anthony James Reb Dooley Guest Star Kim Darby Angel Guest Star James Almanzar Indio Guest Star Royal Dano Rory Luken Guest Star Victor French Eben Luken Guest Star Gregg Palmer Deputy Reed Guest Star John Mantley Producer Calvin Clements Sr. Writer Hal Sitowitz Writer Calvin Clements Jr. Writer Clyde Ware Writer Emily Mosher Writer Norman MacDonnell Producer Arthur Rowe Writer Ron Honthaner Writer Ron Bishop Writer Warren Douglas Writer Robert Totten Director, Writer Vincent McEveety Director Gunnar Hellström Director Richard C. Sarafian Director Irving J. Moore Director John Rich Director David Alexander Director Alvin Ganzer Director