Rachel Bilson Dr. Zoe Hart Actor Jaime King Lemon Breeland Actor Wilson Bethel Wade Kinsella Actor Cress Williams Lavon Hayes Actor Scott Porter George Tucker Actor Gary Cole Dr. Ethan Hart Guest Star Tim Matheson Dr. Brick Breeland Guest Star Ann Cusack Annie Hattenbarger Guest Star Eisa Davis Addy Pickett Guest Star McKaley Miller Rose Hattenbarger Guest Star Kaitlyn Black AnnaBeth Guest Star Claudia Lee Magnolia Breeland Guest Star Ross Philips Tom Long Guest Star Mallory Moye Wanda Guest Star Reginald VelJohnson Dash DeWitt Guest Star Brandi Burkhardt Crickett Guest Star Deborah S. Craig Shelley Ng Guest Star Esther Scott Delma Warner Guest Star Maureen Sebastian Sandi Guest Star Laurel Coppock Peggy Guest Star Zoe Chao Dr. Lee Guest Star Leila Gerstein Executive Producer Josh Schwartz Executive Producer Stephanie Savage Executive Producer Len Goldstein Executive Producer Jason Ensler Executive Producer Jeremiah S. Chechik Director Donald Todd Writer