Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Elias Koteas Jack Moriarty Guest Star Michelle Clunie Judy Guest Star Christian Tallman Vince Guest Star Obie Sims Cuddy's Patient Guest Star Bobbin Bergstrom Nurse Guest Star Gary Grove Puppeteer Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer, Director, Writer Bryan Singer Executive Producer