Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Azura Skye Irene Guest Star Anne Dudek Dr. Amber Volakis Guest Star Olivia Wilde Thirteen, Dr. Remy Hadley Guest Star Peter Jacobson Dr. Chris Taub Guest Star Kal Penn Dr. Lawrence Kutner Guest Star Carmen Argenziano Henry Dobson Guest Star Edi Gathegi Dr. Jeffrey 'Big Love' Cole Guest Star Andy Comeau Dr. Travis Brennan Guest Star Caroline Lagerfelt Connie Guest Star Scott Alan Smith Dr. Brady Guest Star Tom Wright Dr. Pilcher Guest Star Kenneth White Old Man Guest Star Jerry Hauck Martin Guest Star Vince Deadrick Jr. Mr. Franklin Guest Star Jose Vasquez Gang Banger Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Deran Sarafian Director David Hoselton Writer